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Welcome to the lab page of the Brewer/Raghuraman lab. We use genomic tools and the budding yeast Saccharomyces cerevisiae to investigate the regulation of eukaryotic chromosomal DNA replication--how cells choose which origins of replication to use, how they decide when in S phase to fire those origins, and how cells respond to replication stress.

A second, related area of interest is in the evolution of the replication program: How do origins evolve? How does selection act on replication when no single origin is essential for viability? How does the organization of the genome for replication influence the architecture of the genome, and vice versa? To explore such questions, we explore replication and genome structure in related yeasts such as Lachancea waltii (the yeast previously known as Kluyveromyces waltii).

We are committed to the principle that science is for everyone regardless of race, color, religion, sex, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information.  We are committed to fostering a diverse community of scholars that is encouraging and welcoming to everyone.  All members are respected and are expected to contribute to a positive and uplifting training environment. Please see here for a full statement of our values.

Oh, and we enjoy cooking. We love good food. A lot.